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Technologies

Oncobiomed has the exclusive license to develop and distribute TAPCells.

Cancer represents a serious challenge to public health and the global economy, and its incidence continues to rise. In 2020, more than 19.3 million cases were reported, and this figure is estimated to reach 28.4 million by 2040, driven by population growth and ageing.

Oncobiomed Advanced Cell Technology S.p.A., based in Santiago, Chile, is a biotechnology company specialising in the development and technology transfer of cancer vaccines based on immunogenic lysates.. TAPCells® y LycellVax® han sido diseñadas como terapias para cáncer de colon, melanoma,  cáncer de próstata y otros tipos de cáncer. Estas tecnologías ya han completado estudios clínicos de fase I o fase II y han mostrado superioridad respecto a otras terapias por su efectividad clínica de largo plazo, la ausencia de efectos adversos y su adaptación a la realidad económico-social de los países emergentes. 

The global immunotherapy drug market was estimated at USD 284 billion in 2024 and is expected to reach around USD 1.3 trillion by 2033.In this context, Oncobiomed is valued at USD 32 million, and its technologies are estimated to reach projected sales of USD 6 billion for melanoma and USD 27 billion for prostate cancer.    

The success of the immunotherapies developed by Oncobiomed has benefited more than 300 patients, whose clinical results have been published in scientific journals with global impact. The company has also obtained, logrando además la patents to commercialise its technologies in Chile, Australia, New Zealand, the United States, Mexico, Brazil and Israel..

TapCells®

Immunotherapy based on autologous dendritic cells loaded with immunogenic lysates. Personalized vaccine against skin cancer, prostate cancer and other tumors.

LycellVax®

Immunotherapy based on immunogenic cell lysates. Polyvalent vaccine against solid tumors.

Scientific publications

2025 - 2021
2024

Long-Term Survival and Immune Response Dynamics in Melanoma Patients Undergoing TAPCells-Based Vaccination Therapy.

2023

Whole tumour cell-based vaccines: tuning the instruments to orchestrate an optimal antitumour immune response.

2022

Haptoglobin Induces a Specific Proteomic Profile and a Mature-Associated Phenotype on Primary Human Monocyte-Derived Dendritic Cells.

2021

C-type lectin receptors MR and DC-SIGN are involved in recognition of hemocyanins, shaping their immunostimulatory effects on human dendritic cells.

2020
A heat-shocked melanoma cell lysate vaccine enhances tumor infiltration by prototypic effector T cells inhibiting tumor growth.
2019

Dendritic Cells Loaded with Heat Shock-Conditioned Ovarian Epithelial Carcinoma Cell Lysates Elicit T Cell- Dependent Antitumor Immune Responses In Vitro.

2018
Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy.
2018
Molecular signatures associated with tumor-specific immune response in melanoma patients treated with dendritic cell-based immunotherapy.
2018
Tumor lysate-based vaccines: on the road to immunotherapy for gallbladder cancer.
2013

Immunological and Clinical Outcomes of DC-Vaccinated Melanoma Patients Are Associated with Increased Th1/Th17 and Reduced Th3 Cytokine Responses.

2013

Tumour cell lysate-loaded dendritic cell vaccine induces biochemical and memory immune response in castration-resistant prostate cancer patients.

2013

TAPCells, the Chilean dendritic cell vaccine against melanoma and prostate cancer.

2012

Toll-like receptor 4 gene polymorphism influences dendritic cell in vitro function and clinical outcomes in vaccinated melanoma patients.

2011

Heat-Shock Induction of Tumor-Derived Danger Signals Mediate Rapid Monocyte Differentiation into Clinically Effective Dendritic Cells.

2009

Prolonged Survival of Dendritic Cell–Vaccinated Melanoma Patients Correlates With Tumor-Specific Delayed Type IV Hypersensitivity Response and Reduction of Tumor Growth Factor B-Expressing T Cells.

2007

Paradoxical effects of cytokines in tumor immune surveillance and tumor immune escape.

2006

The role of regulatory T lymphocytes in the induced immune response mediated by biological vaccines.

2005

Dendritic cell immunizations alone or combined with low doses of interleukin-2 induce specific immune responses in melanoma patients.

Contact

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Málaga 85, Las Condes
Santiago, Chile
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+56 9 7753 2325

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